Current Funding Announcements

Announcement: Grant
Title:  NIDCD Clinical Research Center Grant (P50/Clinical Trial Optional)
Award Organization: NICD
Type/Mechanism: Grant
Funding Opportunity Number: PAR-19-137
Award Amount: $1.5M/year 
Pre-proposals Due:  7 Jan, 2019
Full App Due: February 6, 2019; June 6, 2019; October 4, 2019; February 6, 2020; June 8, 2020; October 6, 2020; February 8, 2021; June 6, 2021; October 6, 2021


Notes: 
Description: The National Institute on Deafness and Other Communication Disorders (NIDCD) invites applications for Clinical Research Center Grants designed to advance the diagnosis, prevention, treatment, and amelioration of human communication disorders.  For this announcement, Clinical Research is defined as research involving individuals with communication disorders or data/tissues from individuals with a communication disorder. Examples of such research include but are not limited to, studies of the prevention, pathogenesis, pathophysiology, diagnosis, treatment, management or epidemiology of a disease or disorder of hearing, balance, smell, taste, voice, speech, or language.

Applications may propose a clinical trial but are not required (optional).  

Proposed research must meet 4 essential criteria:

1.  Must be clinical as defined above.
2.  Must have a well-defined central unifying theme consisting of three or more research projects with 1 or more supporting cores as appropriate; one core must be an administrative core.
3.  Each project must be unambiguously related to the central unifying theme. Synergistic and substantial interactions among the projects should be evident.
4.  Must provide multidisciplinary approaches to the central theme, defined as having research projects representing different disciplines, approaches and expertise. 

Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-19-137.html

PA-19-053: NIH Exploratory/Developmental Research Grant Program (Clinical Trial Not Allowed) 

PA-19-054: NIH Exploratory/Developmental Research Grant Program (Clinical Trial Required) 

Description: The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. This program is intended to encourage new exploratory and developmental research projects. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

These studies should break new ground or extend previous discoveries toward new directions or applications. Applications for Exploratory/Developmental Research Grant awards should include projects distinct from those supported through the traditional R01 activity code. 

Open Date (Earliest Submission Date): January 16, 2019
Application Due Date(s): February 16, 2019
Expiration Date: January 8, 2022

Information: PA-19-053, PA-19-054

Announcement: Grant
Title: Military Operational Medicine Research Program (Joint Program Committee-5)
Intramural Research Solicitation Notice
Award Organization: Joint Program Committee 5 (JPC-5) Working Groups (WGs)
Type/Mechanism: Grant
Funding Opportunity Number: N/A
Award Amount: Limited and starts in FY 20, contact POC.
CFDA Number: 12.420-Military Medical Research and Development
Pre-proposals Due: 1 Nov, 2018
Full App Due: 23 Jan, 2019

Notes:
Description: Joint Program Committee 5 (JPC-5) Working Groups (WGs) are
currently requesting (intramural) research pre-proposals for fiscal year
2020 (FY20). With funding from the Defense Health Program, JPC-5 established
WGs to provide intramural opportunities to fill research, development, test
and evaluation (RDT&E) gaps in Military Operational Medicine. WG titles,
Chairs, Goals and Objectives can be found in the "JPC-5 Working Groups -
FY20 Goals & Objectives" attachment. Proposed research needs to align to a
WG Goal and Objective. We specifically seek projects proposing research
solutions that will lead to the delivery of materiel or knowledge products
that will be useful to our Service members. Projects involving computational
modeling related to WG Goals and Objectives are also sought after; such
pre-proposals should be submitted to the WG to which they are most closely
tied. Intramural researchers who are submitting pre-proposals from
non-medical laboratories are encouraged to team up with medical laboratory
collaborators. Research in an emerging topic area relevant to military
operational medicine that falls outside of the areas of emphasis outlined in
the "JPC-5 Working Groups - FY20 Goals & Objectives" document will also be
considered.

Working Group research areas of interest include:
Hearing Loss and Vestibular Issues (Chair: MAJ Angela Fulbright)
. Goal 1: Develop joint DoD medical protection and performance
criteria for hearing protection devices (HPDs) in order to improve use of
HPDs by Service members.
. Goal 2: Develop validated auditory and vestibular injury risk
prediction models and tools to detect functional hearing deficits in austere
environments to support hearing surveillance and field fitness for duty
assessments.
. Goal 3: Develop interventions to prevent/mitigate hearing loss and
tinnitus from hazardous noise exposure.

Pre-proposals due: 1 November 2018
Invited full proposals due: 23 January 2019

Max Funding: JPC-5 funding for new starts in FY20 is limited. For more
information on estimated available funds in FY20, please contact Ms. Karie
Abernethy, JPC-5 Program Analyst (karie.e.abernethy.ctr@mail.mil or
301-619-7885).

For more information: Contact Dr. Adam Book at adam.a.book.civ@mail.mil with
questions regarding pre-proposal subject relevance to JPC-5.

Announcement:Grant Title: DoD Psychological Health/ Traumatic Brain Injury, Complex Traumatic Brain, Injury Rehabilitation Research, Clinical Research Award

Award Organization: US Army Medical Research (USAMRAA)

Type/Mechanism:Grant Funding Opportunity Number: W81XWH-18-CTRR-CRA

Web Site: DoD: https://www.grants.gov/web/grants/view-opportunity.html?oppId=308223

Expected Number of Awards: 2

Award Amount: $2,000,000

CFDA Number: 12.420-Military Medical Research and Development

Pre-App Due: 24 Sep, 2018

Full App Due: 17 Dec, 2018

Notes: 

The FY18 PH/TBIRP CTRR-CRA is intended to support clinical research focused on understanding the clinical sequelae and mechanisms of recovery associated with TBI and TBI rehabilitation interventions. The overarching goals of this award are to address TBI-related impairments and deficits, including multimodal, and cognitive dysfunction to (1) develop and validate rehabilitation outcome measures; (2) systematically analyze standard of care cognitive interventions to identify optimal treatment ingredients; and (3) improve clinician-driven assessment strategies to guide return-to-duty decision making.

The FY18 PH/TBIRP CTRR-CRA seeks research to develop and validate novel outcome measures that will characterize and track functional cognitive performance in Service members and relevant populations with cognitive dysfunction following TBI; and to identify key treatment ingredients to optimize cognitive rehabilitation following TBI, as consistent with the mission of the JPC-8/CRMRP.

The proposed research must be relevant to active duty Service members, Veterans, and their beneficiaries. It is expected that any research findings will also provide benefit to the general population.

The FY18 PH/TBIRP CTRR-CRA mechanism supports applied and translational clinical research to advance the development of knowledge and materiel products for rehabilitation and restoration of function following TBI. Applicants should explain how their work will inform the development, refinement, and/or revision of existing standards of care, clinical recommendations, or guidelines.

Announcement: Grant
Title:  DoD Accelerating Innovation in Military Medicine Research Award
Award Organization: US Army Medical Research (USAMRAA)
Type/Mechanism: Grant
Funding Opportunity Number: W81XWH-18-DMRDP-AIMM
Web Site: DoD: https://www.grants.gov/web/grants/view-opportunity.html?oppId=308031
Expected Number of Awards: 6
Award Amount: $3,000,000
CFDA Number: 12.420-Military Medical Research and Development
Full App Due: 2 Jan, 2019

Notes: 
The AIMM Research Award is intended to support highly creative and conceptually innovative high-risk research with the potential to accelerate critical discoveries or major advancements that will significantly impact military health and medicine. AIMM initiative funding supports novel research concepts and other efforts that initiate or enhance potential game-changers that may not be supported by other funding mechanisms or core programs. Applications using synthetic or systems biology-based approaches or focused on autonomous healthcare are highly encouraged.

Description: The United States Army Medical Research Acquisition Activity (USAMRAA), in support of the United States Army Medical Materiel Development Activity (USAMMDA) Tissue Injury and Regenerative Medicine Project Management Office (TIRM PMO), intends to solicit for research and development (R&D) services to develop a pharmaceutical intervention for prevention of permanent noise-induced hearing loss (NIHL) for acute exposure treatment within seventy-two (72) hours of exposure to unanticipated noise hazards common to military operations (e.g., blasts, forgotten ear plugs while on patrol).  The desired status at the end of this procurement action is completion of a Phase 2 clinical trial and an approved Phase 3 clinical study plan, both under an Investigational New Drug (IND) 

The solicitation has been released via FedBizOpps (www.fbo.gov) to the vendor community and will close not earlier than 30 days after the issuance date.  Specifications of the requirement have been provided in solicitation W81XWH-18-R-0025.

Point of Contact:

• Supports highly creative and conceptually innovative high-risk research with the potential to accelerate critical discoveries or major advancements that will significantly impact military health and medicine
• Supports novel research concepts and development of enabling technologies; not intended to support incremental advances on previous or ongoing work
• Supports applied research efforts that initiate or enhance potential game-changers; clinical trials are not allowed.
• Projects proposed should be relevant to at least one DoD medical research program area. Cross-cutting research projects with the potential to benefit multiple DoD medical research program areas are highly encouraged.
• Applications using synthetic or systems biology-based approaches are highly encouraged
• Preliminary data that are relevant to the proposed research are encouraged, but not required.
• Preproposal is required; application submission is by invitation only

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcement and General Application Instructions that will be available for electronic downloading from the Grants.gov website at https://grants.gov. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all USAMRMC funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

Applications must be submitted through the federal government’s single-entry portal, Grants.gov. Submission deadlines are not available until the Program Announcement is released. For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about other CDMRP-administered programs, please visit the CDMRP website (http://cdmrp.army.mil).

Point of Contact:

CDMRP Public Affairs
301-619-9783
usarmy.detrick.medcom-cdmrp.mbx.cdmrp-public-affairs@mail.mil

Applicants requesting $500,000 or more in direct costs in any year (excluding consortium F&A) must contact a Scientific/ Research Contact at least 6 weeks before submitting the application and follow the Policy on the Acceptance for Review of Unsolicited Applications that Request $500,000 or More in Direct Costs as described in the SF424 (R&R) Application Guide

Pre-award costs are allowable only as described in the NIH Grants Policy Statement.

Closing Dates:

Competition closes @midday     Decision date           Feedback released         

19 March 2018                        31 May 2018            28 June 2018     

21 May 2018                           6 August 2018          6 September 2018          

31 August 2018                      31 October 2018        28 November 2018         

15 October 2018                    20 December 2018     31 January 2019

4 January 2019                     12 March 2019            12 April 2019      

1 March 2019                        30 May 2019              28 June 2019      

Notes: Description: The Open Call is looking for innovative ideas on how we can improve the defense and security of the UK. Your idea could be a concept, product or service, at various levels of maturity. The Accelerator is open to all. Submissions are welcome from all organization types and individuals. There are no nationality restrictions.

Defense innovations can apply to any part of defense, and can include technological solutions as well as product, service or process ideas.