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Current Funding Announcements

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PRE-ANNOUNCEMENT: Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Toxic Exposures Research Program (TERP) Anticipated Funding Opportunities for FY22

PRE-ANNOUNCEMENT: Department of Defense Congressionally Directed Medical Research Programs (CDMRP) 
Toxic Exposures Research Program (TERP)Anticipated Funding Opportunities for FY22


Description: The Consolidated Appropriations Act, 2022 provides funding for the TERP to support 

innovative, high-impact toxic exposures research. This pre-announcement to allow investigators time 
to plan and develop ideas for submission to the anticipated FY22 funding opportunities. The FY22 
TERP funding opportunity announcements for the following award mechanisms will be posted on the website. Pre-application and application deadlines will be available when the 
announcements are released.

Applications must address one or more of the Program Goals:

•    Elucidate mechanisms of how toxic exposures result in adverse effects
•    Diagnose the effects of toxic exposures
•    Predict and prevent toxic exposures
•    Develop therapeutics, treatments, and strategies


Applications must address one or more Topic Areas, which include Neurotoxin Exposure (e.g., 
long-term disorders, basic mechanisms, prediction/prevention/assessment, innovative treatments, 
clinical signs and symptoms or biomarkers, comorbidities). Any proposed exposure must be relevant 
to Service Members, Veterans and/or the American public. Areas of encouragement include exposures 
to fuels and other petroleum products.

Pre-announcement news release:

About TERP:

Anticipated maximum funding/periods of performance

     •    Investigator Initiated Research Award (IIRA): $500,000/3 years
     •    Translational Research Award (TRA)
           o $800,000/3 years
           o Partnership option: $1.6M/3 years
     •    Clinical Trial Award (CTA)
           o $1.5M/4 years
           o Partnership option: $2.5M/4 years

Point of Contact: CDMRP Public Affairs, 301-619-9783,


fy 22 traumatic brain injury and psychological health research program (TBIPHRP)

W81XWH-22-TBIPHRP: FY22 Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP)

Description: The FY22 Defense Appropriations Act provides funding for TBIPHRP to support research 
into the treatment, prevention, and detection of traumatic brain injury (TBI) and improved 
psychological health. The TBIPHRP’s vision is to optimize the prevention, assessment, and treatment 
of psychological health conditions and/or traumatic brain injuries. Proposed research can be 
aligned with TBI, psychological health, or both. The program seeks to fund research that 
accelerates solutions to improve the health, well-being, and healthcare of Service Members, 
Veterans, military beneficiaries, and the American public. Applications must address one or more 
Focus Areas, not all of which will be applicable to every award mechanism:

•     Understand: research will address knowledge gaps in foundational science, epidemiology, and 
etiology of psychological health conditions and/or TBIs.
•     Prevent and Assess: research will address the prevention or progression of psychological 
health conditions and/or TBI through population, selective, and indicated prevention approaches, 
including efforts that focus on primary prevention, screening, diagnosis, and prognosis.
•     Treat: research will address immediate and long-term treatments and improvements in systems 
of care, including access to and delivery of healthcare services. Treatment topics may include 
novel treatments and interventions, personalized medicine approaches, length and durability of 
treatment, rehabilitation, relapse, and relapse prevention. Includes interventions focused on 
sensory and motor dysfunction after brain injury.

Maximum funding/periods of performance:
Clinical trial award (CTA)
•     Pre-application due September 1, 2022; full application due December 8, 2022
•     Funding level 1: $500,000/3 years
•     Funding level 2: $2M/4 years
•     Funding level 3: $4M/4 years Focused program award (FPA)
•     Pre-application due September 1, 2022; full application due December 8, 2022
•     $5M/4 years
Investigator initiated research award (IIRP)
•     Pre-application due August 24, 2022; full application due September 14, 2022
•     $500,000/3 years Translational research award (TRA)
•     Pre-application due August 24, 2022; full application due September 14, 2022
•     $1M/3 years
Patient-centered research award (PCRA)
•     Pre-application due August 24, 2022; full application due September 14, 2022
•     $1M/4 years
Full announcements and additional information are available at:

Congressionally Directed Medical Research Programs (CDMRP) Hearing restoration research program (HRRP) - FY 22 focused research award

W81XWH-22-HRRP-FRA: Congressionally Directed Medical Research Programs (CDMRP) Hearing Restoration 
Research Program (HRRP) – FY22 Focused Research Award


Description: The FY22 Defense Appropriations Act provides funding for the Hearing Restoration 
Research Program (HRRP) to support innovative and impactful research that pursues the treatment of 
auditory system injuries and the restoration of hearing. About HRRP: To meet the intent of the award mechanism, all applications to 
the FY22 HRRP Focused Research Award (FRA) must address research in one or more of the following 
Focus Areas:
•    Accelerate translation of biological regeneration/repair mechanisms into therapies that treat 
auditory system injury and restore auditory function, for example:
     o Hair cell regeneration/repair/recovery
     o Neural regeneration/repair/recovery
     o Treatment for synaptopathy and hidden hearing loss
•    Diagnostic tests that help differentiate sensory, neural, synaptic, and central processing 
disorders, that may inform applicability and outcomes for current or future hearing restoration 
•    Develop reliable in-vitro human models to facilitate the understanding, derivation, and 
characterization of human auditory cells, and/or to facilitate the evaluation of hearing 
restoration therapies.
•    Develop and/or validate techniques/methods beyond the audiogram to diagnose acute auditory 
system injury in austere or remote environments. For example, but not limited to, simple and rapid 
assessments that are compatible with portable platforms.
Tinnitus or vestibular-related research is excluded.
A pre-application is required and must be submitted through the electronic Biomedical Research 
Application Portal (eBRAP) at prior to the pre-application deadline. All 
applications must conform to the final funding opportunity announcements that will be available for 
downloading from the website.


Pre-Application Submission Deadline: July 22, 2022 (5:00 p.m. Eastern)
Application Submission Deadline: November 30, 2022 (11:59 p.m. Eastern)


Maximum funding/periods of performance:
     Funding level 1: $250,000/2 years
     Funding level 2: $1M/3 years
     Funding level 3: $1.25M/3 years

Combat Readiness – Medical Research Program Rapid development and translational research award (RDTRA)

Description: The CRRP focuses on forward-deployable solutions that can promptly address life- 
threatening injuries, medical threats, and treatments for Warfighters in current and future 
battlefield settings, to deliver high-impact medical solutions in diverse operational settings and 
closer to the point of injury to increase survivability and Warfighter readiness. The program seeks 
to develop innovative solutions to increase medical readiness, mitigate fatalities, optimally treat 
life-threatening injuries, and promote positive long-term outcomes.  Innovations developed by 
CRRP-supported research may be applied proactively as a way to establish medical readiness ahead of 
deployment, in operational settings at the point of injury, during periods of prolonged care, or 
during transport/ en route between roles of care.
Focus Areas broadly describe current priorities to improve readiness for delivering frontline care 
in combat situations and for delivering medical damage control capability, assets, and life- saving 
interventions during prolonged and en route care in austere and combat environments, including the 
acute and early management of combat-related trauma at the point of injury.
Proposed research must address at least one of the FY22 CRRP Focus Areas; these include 
complementary health measures to accelerate return to duty, and regenerative medicine. Focus areas 
include solutions to enhance combat care delivery throughout the far-forward environment, such as:
•    Telemedicine solutions that enable medical capabilities at far-forward battlespace locations 
•    Medical simulation technology that supports sustainment of critical skills and medical 
•    Solutions for the assessment of mild traumatic brain injury, to include portable and handheld 
Proposed research must have the potential for rapid development and translation of applicable 
advances for improving medical readiness, mitigating fatalities, optimally treating life- 
threatening injuries, and promoting positive long-term outcomes for military health and medicine, 
as well as the general public. Supports preclinical research, clinical research, and small-scale 
clinical trials (e.g., first in human, phase 1/1b).

Pre-Application (Preproposal) due: June 23, 2022
Proposal/Application due: September 14, 2022
Max Period of Performance: 2 years (3 years with option)
Max Funding: $2.2M total costs (2 years), $1M option year


For more information, full announcements (extramural, intramural), and submission

BRAIN Initiative: Targeted BRAIN Circuits Projects – Targeted BCP (R01 Clinical Trial Not Allowed)

RFA-NS-22-026: BRAIN Initiative: Targeted BRAIN Circuits Projects – Targeted BCP (R01
Clinical Trial Not Allowed)
Description: This FOA solicits applications for research projects that seek to understand how 
circuit activity gives rise to mental experience and behavior using innovative, methodologically- 
integrated approaches. The goal is to support adventurous projects that can realize a potentially 
transformative outcome within 5 years. Applications are expected to address circuit function in the 
context of specific behaviors or neural systems, such as sensation, perception, attention, 
reasoning, intention, decision-making, emotion, navigation, communication, or homeostasis. Projects 
should link theory, data analysis, and/or computational approaches to experimental design and 
should produce predictive models (conceptual or quantitative).
Projects should aim to improve the understanding of circuits of the central nervous system by 
systematically controlling stimuli and/or behavior while actively recording and/or manipulating 
dynamic patterns of neural activity. Diverse species or experimental systems and a cross- 
species/comparative approach are welcome and should be chosen based on their power to address the 
specific question at hand and to reveal generalizable and fundamental neuroscience principles.
Targeted BRAIN Circuit Project R01 awards will support an individual laboratory or a small 
multi-PD/PI team. Projects should reflect the NIH BRAIN Initiative interests of the application of 
cutting-edge methodologies to understand central nervous system circuit function and
dynamics at cellular and sub-second levels of resolution in ethologically relevant behaviors of an 
organism or a well-defined neural system. Applications should offer specific, feasible, and 
potentially transformative research goals as endpoints within a 5-year term


Representative topics include: Innovative approaches to understand network coding of sensory 
information and/or multi-sensory integration, at multiple stages of processing, in response to 
naturalistic inputs and perceptual contexts.


Letter of Intent due date(s) 30 days prior to the application due date
Application due dates: June 1, 2022; July 1, 2022; October 6, 2022; June 30, 2023; October 4,
2023; June 28, 2024; October 2, 2024
Maximum project period: 5 years
Funding amount: the BRAIN Initiative intends to commit up to an estimated total of $15 M per year 
to fund 20 awards.



NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01 Clinical Trials Optional)

RFA-DC-22-001: NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01 Clinical Trials Optional)
NIH - National Institute on Aging (NIA) and National Institute on Deafness and Other Communication 
Disorders (NIDCD)
Description: This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic 
scientists, clinicians and clinical scientists to jointly initiate and conduct translational 
research projects which translate basic research findings into clinical tools for better human 
health. The scope of this FOA includes a range of activities to encourage translation of basic 
research findings which will impact the diagnosis, treatment and prevention of communication 
disorders.  Connection to the clinical condition must be clearly established and the outcomes of 
the grant must have practical clinical impact.

Possible goals include, but are not limited to:

•     Biochemical, electrophysiological and behavioral assays to enhance diagnostic capabilities.
•     Pharmacology, toxicity, and pharmacokinetic for candidate therapeutics that have demonstrated 
potential for the treatment of communication disorders.
•     Preclinical animal research for dosage studies and toxicity when a subsequent Phase I/II 
clinical trial is planned.
•     Translation of new tools and techniques for better diagnostics or therapeutics, including but 
not limited to, neuroprosthetic devices, drug delivery devices, neuro-electrical stimulators and 
recording devices.
•     Translation of laboratory-based screening tests, including biomarkers into improved ways to 
identify individuals at risk for a communication disorder to allow for early intervention.
•     Translation of published basic research findings into new clinical tools to better target the 
treatment to the individual patient and to better predict patient response or prognosis.
•     Translation of discoveries from biological, psychological, social sciences and other related 
areas into innovative prevention and treatment paradigms and processes.
•     Modification of laboratory measures of function or laboratory treatment protocols for use in 
clinical settings.
Open Date (Earliest Submission Date): September 17, 2021
Letter of Intent Due Date(s): 30 days prior to the application due date
Application Due Date(s): October 20, 2021; June 20, 2022; February 22, 2023; October 18,
2023; June 20, 2024
Maximum Project Period: 5 years
Maximum Amount: NIDCD anticipates funding an estimated 2-3 awards in fiscal year 2022 for a total 
of $1,500,000.

Open/Active DoD Broad Agency Announcements

U.S. Army Medical Research and Development Command (USAMRDC) - W81XWH18SBAA1: This BAA is open through September 30, 2022. USAMRDC funds a broad range of extramural research programs through contracts, grants, or cooperative agreements. Proposals can be submitted through the USAMRDC Broad Agency Announcement (BAA) or through special USAMRDC BAA Announcements, which are open for limited timeframes. Additional information, the USAMRDC Broad Agency Announcement, and open special USAMRDC BAA Announcements can be obtained at: and


U.S. Military Academy Broad Agency Announcement - W911NF-20-S-0008: This BAA was released April 1, 2020, and is open until March 31, 2025. It seeks proposals for cutting- edge innovative research that could produce discoveries with significant impact to enable new and improved Army technologies and related operational capabilities in the areas of socio-cultural; information technology; ballistics, weapons and protections; energy and sustainability; materials, measurements, and facilities; unmanned systems and space; human support systems; and artificial intelligence, machine learning, and quantum technologies. The human support systems focus includes biomechanical engineering to enhance soldier readiness (human performance optimization, injury prediction/prevention, physical and cognitive augmentation, Return-to-Duty metrics, functional influence of prosthetics/exoskeletal devices) and wearable technologies and sensors to inform performance decisions (e.g., monitoring/assessment, injury prevention, recovery times). 

              See:  Military Academy BAA

Research Interests of the Air Force Office of Scientific Research

Announcement: BAA-AFRL-AFOSR-2016-0007
Award Organization: Air Force Office of Scientific Research
Type/Mechanism: Grant
Activity Code: 
Web Site: DoD:
Award Amount: $200,000 - $400,000 encouraged; $7.5M max
PoP: 5 years
Restrictions: None
Rolling Annual Programs: Open until Superseded
Pre-Application Due: Open until superseded
Full App Due: Open until superseded
Notes: For the sensory systems portion of the portfolio a goal is to pursue new capabilities in acoustic analysis, to enhance the intelligibility and usefulness of acoustic information. The primary approach is to discover, develop, and test principles derived from an advanced understanding of cortical and sub-cortical processes in the auditory brain. Included are efforts to model and control effects of noise interference and reverberation, understand the psychoacoustic basis of informational masking, develop new methods for automatic speech detection, classification, and identification, and enable efficient 3D spatial segregation of multiple overlapping acoustic sources.

DOD USAMRMC FY18-FY22 Broad agency announcement for extramural medical research

Announcement: W81XWH18SBAA1
Award Organization: U.S. Army Medical Research and Material Commnad's
Type/Mechanism: Grants Notice
Activity Code: USC, Title 10, Section 2358
Web Site:
Award Amount:  
PoP: 4 years 
Rolling Annual Programs:
Pre-Application Due: Oct 1, 2017
Full Application Due :  September 30, 2022, 11:59 p.m. ET
Notes: Clinical and Rehabilitative Medicine Research Program focus on the innovations required to reset our wounded Service members, both in terms of duty performance and quality of life. Innovations developed from CRMRP-supported research efforts are expected to improve restorative treatments and rehabilitative care to maximize function for return to duty (RTD) or civilian life. 
The CRMRP focuses its efforts on the following research areas: neuromusculoskeletal injury (including limb trauma and amputation), sensory systems impairment (including hearing, balance, tinnitus, and vision), acute and chronic pain, and regenerative medicine.

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The Hearing Center of Excellence fosters and promotes the prevention, diagnosis, mitigation, treatment, rehabilitation and research of hearing loss and auditory injury. It supports the development, exchange and adoption of best practices, research, measures of effectiveness and clinical care guidelines to reduce the prevalence and cost of hearing loss and tinnitus among Warriors and Veterans. Read more

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