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Female service members stand on the flightline for Women's History Month at Nellis Air Force Base, Nevada, March 19, 2021. The service members participated in the Air Force's two-week advanced aerial combat training exercise, Red Flag. (U.S. Air Force photo by Airman 1st Class Natalie Rubenak)
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Uterine Cancer

Uterine Cancer is a type of pelvic cancer. Uterine cancer affects the structures and organs in the pelvis. The pelvic area is the lower portion of the trunk of a genetic female body. The pelvis contains the:

  • Pelvic bones
  • Bladder
  • Rectum
  • Reproductive organs

Uterine cancers can be either:

  • Endometrial cancer (common) or
  • Uterine sarcoma (rare)

Endometrial cancer is curable. Uterine sarcoma is more aggressive and it’s harder to treat.

Risk Factors

These factors may increase your chance of getting uterine cancer.

  • Being over 50 years old
  • Being obese
  • Taking only estrogen for hormone replacement during menopause
  • Having trouble getting pregnant
  • Having less than five periods in a year before starting menopause
  • Taking Tamoxifen
  • Having close family members who have had:
    • Uterine cancer
    • Colon cancer
    • Ovarian cancer


You can’t prevent uterine cancer, but you can lower your chance of getting it. This includes:

  • Pregnancy and breast-feeding. Estrogen levels are lower during pregnancy. Estrogen levels are also lower when breast-feeding. The risk of endometrial cancer is also lower in women who’ve had children. Breastfeeding also decreases the risk of endometrial cancer.
  • Combining estrogen and progestin. This is found in combined oral contraceptives.
  • Losing weight
  • Being physically active
  • Maintaining a healthy weight
  • Using combined hormone therapy instead of estrogen-only hormone therapy


Signs and symptoms of uterine cancer include:

  • Vaginal discharge
  • Vaginal bleeding
  • Pelvic pain
  • Pelvic pressure
Last Updated: August 08, 2023
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