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Neurologic Adverse Events

See the following for more information about neurologic adverse events.


Acute Disseminated Encephalomyelitis

ADEM is an intense autoimmune disease that produces multiple inflammatory lesions in the brain and spinal cord that damages nerve fibers. ADEM occurs in fewer than 1 (0.8) per 100,000 people per year.

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Transverse Myelitis

Acute transverse myelitis is acute inflammation of gray and white matter across both sides of one or more adjacent spinal cord segments. Damage will affect function at that segment and segments below it. The cause of ATM is unknown.

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Guillain-Barré Syndrome

GBS is a rare disorder in which the body's immune system attacks the nerves to the legs and arms. GBS occurs in about 1 or 2 people per 100,000. It usually presents as a weakness in the legs that spreads upwards to the arms, chest, and the face. Guillain-Barré is one of the leading causes of non-trauma-induced paralysis.

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Brachial Plexus Neuritis

Acute brachial plexus neuritis is an uncommon inflammatory condition of the nerves in the shoulder that leads to severe shoulder and upper arm pain followed by marked upper arm weakness. Brachial neuritis occurs in about 1 to 2 cases per 100,000 persons, but this figure is probably low because many cases may be misdiagnosed, or the symptoms are mild and clinically unrecognized.

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Last Updated: July 19, 2023
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